Painting: Pablo Picasso. Science and Charity. 1897. Oil on Canvas. 197 x 249.5 cm. Picasso Museum, Barcelona.

Research Program Overview

Our research program focuses on clinical and basic investigation in lung disease.  Our overriding mission is to translate our basic research discoveries for a better understanding of the pathogenesis of lung disease and as a way to identify novel and effective treatments for lung disease. 

We benefit from collaborations with many basic science departments in the university and clinical divisions in the Department of Medicine to broaden and strengthen our basic and clinical research. For example, PCCM faculty have ongoing active collaborations with Dr. Marlene Rabinovitch, Professor of Pediatric Cardiology, in the study of pulmonary hypertension; Dr. Irving Weissman, Professor of Pathology, in the study of lung cancer stem cells, and Dr. David Lewis, Professor of Immunology, in the study of cytomegalovirus (CMV) on lung transplant rejection. 

The basic investigative work of Drs. Glenn Rosen and Peter Kao focuses on analysis of signal transduction pathways involved in the pathogenesis of lung cancer, pulmonary hypertension, and fibrotic lung disease.  Dr. Michael Gould has a robust clinical investigative program focusing on lung cancer in deep venous thromboembolism.  The additional clinical investigative programs of Dr. Roham Zamanian in pulmonary hypertension, Dr. Stephen Ruoss in non-tuberculous mycobacterial disease, and Dr. Ann Weinacker in ICU outcomes research complement the basic studies in these areas and extend the findings to patients. 

Our NIH T32 training grant offers trainees the opportunity to develop expertise in clinical investigation by obtaining a Masters in Clinical Epidemiology followed by clinical investigation with a mentor in our division, a mentor in health research policy or basic research in our division, or with a mentor involved in lung-related research in the Department of Medicine or basic science divisions in the university.  We will continue our integrative and collaborative research to enhance our ability to translate basic research findings and improve the treatment of patients with respiratory disease.